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Treatments/Oxaloacetate
OAA

Boost energy levels without a prescription

By going through RTHM Direct, you save $100 per bottle of 90 capsules of Oxaloacetate 500mg.

Only pay if your prescription is approved

How does it work?

Access to medications as easy as 1-2-3

Step 1Step 1
Fill out a condition assessment.
Share your symptoms, current conditions, allergies and complete a health assessment.
Step 2Step 2
Our clinicians will review your health profile.
An expert clinician from RTHM’s provider team will review your case and prescribe if appropriate.

Pay zero fees if you're not approved.

Step 3Step 3
Get approved and pick up your prescription.
Pick up and pay for the prescribed treatments at your pharmacy. Start your treatment in as early as 1 business day.

Affordable Access to Oxaloacetate

RTHM Direct
Online assessment fee for prescription
Only pay if prescription is approved
$0
Pharmacy Cost
Estimated 90 day supply price
you pay at pharmacy
$399
Estimated Total for 90 days
With the RTHM
discount
$399

Key Benefits

Reduce Mental Fatigue
A randomized placebo-controlled study showed that ME/CFS patients taking oxaloacetate experienced a >25% reduction in fatigue, with 40% of participants being “super responders” showing fatigue reductions up to 63%.
Boost Energy Levels
In an open-label study, oxaloacetate reduced mental and physical fatigue by up to 33% in ME/CFS patients and up to 46.8% in Long COVID patients over six weeks.
Enhance Overall Health
Oxaloacetate improves mitochondrial energy production, regulates blood glucose, and exhibits anti-cancer properties, supporting metabolic health and overall well-being.

Is Oxaloacetate right for me?

Oxaloacetate may help with:

  • Fatigue and low energy
  • Brain fog
  • Post-exertional malaise (PEM)
  • Exercise intolerance
  • Neuroinflammation

Patients with ME/CFS, Long COVID, or other conditions linked to mitochondrial dysfunction may benefit from oxaloacetate.

What Does the Research Say?

What People Are Saying About Their Experience with Oxaloacetate

It’s helped me. But I do build up a tolerance sometimes. Some people use it only for crashes. It can really help but it’s not a fix.
ANDHarrisonreddit.com
It helps me so much. Like, so much. I take the benagene for mecfs and take 1000mgs a day. I’ve noticed that it makes my energy envelope a little bit more stretchy, like I can push a little bit and be okay. I’ve been pacing religiously but it seems oxoloacetate increases the gains made from pacing, perhaps even multiplying them? It’s hard to tell, but I’m steadily improving and oxoloacetate is a big part of that.
Thesaltpacketreddit.com
It has helped me! I’ve taken it for over 3 months at the recommended dose. When I had tried it at a lower dosage it did nothing. I’ve been able to stop using my wheelchair. I’ve been able to visit with friends. It’s the only thing that has helped me. The cost is immense. I’m fortunate to have the resources. I’m hoping that it’s something that I tell enough docs about that it’s helping, the more research will continue and it can become accessible through at least insurance.
ANDHarrisonreddit.com

Safety Is Our Top Priority

llene S. Ruhoy

llene S. Ruhoy

MD, PhD, Neurologist

Sarah Almilli

Sarah Almilli

PharmD, APh., IA, Clinical Pharmacist

Stuart Malcolm

Stuart Malcolm

MD, Internist

Jennifer Curtin

Jennifer Curtin

MD, Internist

1. All treatments, including pyridostigmine, are carefully reviewed by RTHM clinicians and pharmacists.

2. We use dosing protocols designed to minimize side effects and ensure safe use.

3. Comprehensive treatment guides are vetted by our expert clinical team.

As you navigate your health journey, we're here to provide safe and effective care.