Explore our range of treatments
Eliminate the stress of finding treatment options that are right for you. RTHM Direct connects you to the latest promising treatments for managing complex illness symptoms.
Don’t know where to start? Our treatment discovery tool can help you find treatment matches for you.
Brain Fog
Brain fog is a type of cognitive dysfunction characterized by poor memory, difficulty focusing, confusion, and mental fatigue.
People experiencing brain fog often describe their thinking as sluggish or “fuzzy,” and they find it challenging to form coherent thoughts or translate those thoughts into words.
Brain fog can be a symptom seen with many conditions including Long COVID, ME/CFS, autoimmune diseases, and nutritional deficiencies.
Low Dose Naltrexone
Low Dose Naltrexone
PEM Headaches Air Hunger Chest Pain Palpitations Sleep Dizziness Orthostatic intolerance Exercise intolerance Sweating
Anti-inflammatory mechanisms in low-dose naltrexone help protect the brain and support clearer thinking and overall cognitive improvement.
Guanfacine
Guanfacine
Coming Soon
Brain fog Palpitations Sleep Dizziness Orthostatic intolerance
Guanfacine, originally approved by the FDA for treating ADHD, has shown promise in mitigating or even eliminating brain fog in patients with Long COVID or other common comorbidities.
Fatigue and PEM
Fatigue is a pervasive feeling of extreme tiredness or lack of energy. It goes beyond normal tiredness and can significantly impact daily life. In conditions like myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), fatigue is a hallmark symptom. However, in ME/CFS, fatigue is not just ordinary tiredness; it’s often severe and debilitating.
Post-exertional malaise (PEM) is a hallmark symptom of (ME/CFS). Patients experience a sudden drop in energy and exacerbation of all symptoms after even the smallest of activities. It occurs after even minor physical or mental exertion. Within 12 to 48 hours after an activity, symptoms worsen significantly. The effects can last for days or weeks.
Low Dose Naltrexone
Low Dose Naltrexone
PEM Headaches Air Hunger Chest Pain Palpitations Sleep Dizziness Orthostatic intolerance Exercise intolerance Sweating
Anti-inflammatory mechanisms in low-dose naltrexone help protect the brain and support clearer thinking and overall cognitive improvement.
Pyridostigmine
Pyridostigmine
Fatigue PEM Brain fog Palpitations Muscle pain Orthostatic intolerance Exercise intolerance Sweating
Pyridostigmine (mestinon), an acetylcholinesterase inhibitor, has shown promise in the treatment of dysautonomia, ME/CFS, and Long COVID by improving autonomic dysfunction, reducing fatigue, and alleviating post-exertional malaise.
Orthostatic Intolerance
Orthostatic intolerance (OI) is an abnormal response to being upright that can cause dizziness, fainting, and other symptoms. These symptoms typically arise when you first stand up and are often due to an abnormal drop in blood pressure or a significant increase in heart rate.
When you recline or sit down, the symptoms usually subside. OI often involves persistent symptoms, including nausea and neurocognitive deficits. Orthostatic intolerance is a subcategory of dysautonomia and often overlaps with conditions like ME/CFS, Long COVID, Ehlers-Danlos, and fibromyalgia.
Treating orthostatic intolerance can often times have multisystemic benefits to the rest of symptoms associated with complex conditions.
Propranolol
Propranolol
PEM Shortness of Breath Headaches Chest pain Palpitations Sleep Dizziness Orthostatic intolerance Exercise intolerance Sweating
Beta-blockers, such as Propranolol, effectively lower heart rate and improve symptoms in patients with dysautonomia, including postural orthostatic tachycardia syndrome (POTS).
Ivabradine
Ivabradine
Coming Soon
PEM Shortness of Breath Palpitations Chest pain Dizziness Exercise intolerance
Ivabradine has emerged as a promising treatment for patients with Long COVID who experience symptoms of dysautonomia, such as palpitations, fatigue, and exercise intolerance.
Mast Cell Activation
Mast cell activation occurs when the mast cells in the body release excessive chemicals, including histamine, leading to allergy symptoms and various other manifestations.
These symptoms can affect the skin (itching, hives, swelling), lungs (wheezing, shortness of breath), and gastrointestinal tract (diarrhea, abdominal pain). Mast cell activation triggers can include infections, stress, medications, and certain foods.
Long COVID risk reduction
Adopting healthy lifestyle choices such as quitting smoking, maintaining a balanced diet, regular exercise, and attending regular health checkups can significantly reduce the risk of developing chronic conditions like heart disease, diabetes, and cancer.
When it comes to developing Long COVID, avoiding an acute COVID infection is the best course of action, however, this isn’t always possible. Certain medications, however, given during an acute COVID infection can help to reduce your risk of Long COVID significantly.
Didn’t find a treatment?
We are continuously vetting and adding new treatments based on the latest research and treatment profile. Let us know what you are looking for and we will take it into account for future developments.
Don’t know where to start?
We can help!
Our treatment discovery tool takes in your symptoms and their severity levels and provides a tailored list of medications that may support your journey back to health.
Get personalized suggestions based on your specific symptoms and conditions and save time sifting through countless research papers.
90-day prescriptions with every consultation.
Following your first month of treatment and before prescribing the next 60-day supply, we may require you to contact your clinician to ensure your medication is working as intended and you’re not experiencing unwanted side effects. To request a new 90-day prescription, you’ll need to schedule a consultation to obtain a refill and renewal.
And in case you missed anything.
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At this time, RTHM Direct requires a diagnosis from a primary clinician or specialist.
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The RTHM DIrect consultation fee is only charged after you have been approved for a prescription.
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At this moment, we do not have the ability for patients to schedule a recurring order for medications. Most medication flows will provide patients with a 90-day supply, although some will require the patient to check in on their experience before sending refills to the pharmacy. When your medication begins to run low, simply come back to the dashboard and fill out a new assessment.
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Once you submit your online assessment, a RTHM Direct provider will review the information and, if a prescription is medically appropriate for your case, they will send the prescription to the pharmacy of your choice. Once the pharmacy receives the prescription, fulfillment is based on the pharmacy's schedule and availability.
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RTHM Direct does not require you to obtain a referral from your primary care provider. That said, we are in no way a replacement for your primary care provider, and we recommend you continue your relationship with them as you start a new treatment from RTHM Direct.
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You should receive an update from your medical provider within 24 hours after your completed qualification assessment. If you completed your qualification assessment after 17:00 PT (Pacific Time), you will receive an update the following day.
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We’re sorry to hear you’re experiencing side effects. For some medications, it’s common to experience mild side effects during the first few days or weeks as your body adjusts. You can read about your medication's common side effects in the clinical summary we sent to your email. If you’d like to talk to a medical provider about your concerns, please log in to your patient dashboard and select “Ask a follow-up question” in the support section.